Clinical Expert, Onco-Immunology

Bioptimus is building the first universal AI foundation model for biology to fuel breakthrough discoveries and accelerate innovation in biomedicine. With more than $75M in funding, Bioptimus is a fast-growing start-up headquartered in Paris, incorporated in October 2023. Backed by leading international venture capitalists, our world-class team of scientists and engineers is redefining the frontiers of AI and life sciences.

This is a remote role. We’re headquartered in Paris, but the position can be performed remotely outside of Paris.

About the role

We are looking for a meticulous and detail-oriented Biology Data Quality Engineer to ensure the integrity and usability of the various and complex datasets that are central to our mission. In this critical role, you'll leverage your expertise in biology, data science, and machine learning to ensure the quality and consistency of biological data used to train and evaluate our foundation models. You'll work in collaboration with the R&D team and our engineers, using your skills to ensure our data meets the highest standards.

What you'll be doing

As a Biology Data Quality Engineer, you will own the following tasks:

• Data Validation Pipeline Development: Develop and implement comprehensive data validation protocols for diverse biological datasets (histology, omics, clinical). Ensure data integrity, consistency, and accuracy through rigorous quality checks. Design and implement automated data quality pipelines to streamline data validation and identify potential issues early in the data processing workflow.
• Data Curation & Standardization: Establish and enforce data standardization practices to facilitate seamless integration and analysis across different data types. Curate datasets to enhance their usability for machine learning.
• Collaboration & Communication: Work closely with the R&D team to understand data requirements and address data quality concerns. Communicate data quality findings and recommendations effectively to technical and non-technical stakeholders. Communicate and synchronize with external data providers.
• Documentation & Reporting: Maintain a detailed documentation of the data-quality assessment procedures, validation results, and data specifications. Generate regular reports on data quality metrics and trends.
• Data Source Evaluation: Evaluate and validate external public data sources, ensuring they meet our quality standards and are suitable for inclusion in our foundation model training.
• Continuous Improvement: Stay up-to-date with the latest data quality best practices and tools in the biological domain. Propose and implement improvements to our data- quality assessment processes and pipelines.
  
  

What you'll bring

The successful candidate will have a ‘team-first’ kind of attitude; be independent, curious, and detail-oriented; thrive in a dynamic, fast-paced environment; and be fun to work with. We value individuals who bring strong domain expertise in biology alongside strong computational, hands-on skills.

• Omics Data Expertise. Deep understanding of transcriptomics data types (bulk, single-cell, spatial) and their specific quality considerations. Good knowledge of genomics and proteomics data.
• Data Quality Management: Proven experience in implementing data quality control procedures and pipelines. Familiarity with data validation tools and techniques.
• Analytical Skills: Strong analytical and problem-solving skills to identify and resolve data quality issues.
• Programming & Data Analysis: Proficiency in Python, good knowledge of data visualization libraries (e.g. matplotlib).
• Communication Skills: Excellent written and verbal communication skills to effectively convey data quality findings and recommendations.
• Educational Background: MSc in Biology, Computational Biology, Bioinformatics.
  
  

How to stand out:

• Computational Pathology Data Expertise: Experience in machine learning analysis of histology images.
• Cloud expertise: Experience working with AWS.
• Data Annotation Experience: Experience with developing and implementing data annotation guidelines and processes. Experience with data ontologies.
• Proven experience building or contributing to large-scale data collections (e.g. Human Cell Atlas).
• Spatial alignment of multimodal datasets (e.g. alignment between different imaging modalities)
  
  

The candidate journey

To be considered, please submit your CV in English. We believe in a transparent and collaborative interview process. Here is what you can expect after submitting your application:

Screening: Once you have applied, the hiring team will review your application to determine if your work experience and skills align with the necessary proficiencies of this position.

Hiring Manager (30 min): A discussion with the Hiring Manager focused on your clinical and translational research background, scientific expertise, and motivation for collaborating with Bioptimus.

Strategic Case Study Discussion (60 min): A collaborative discussion with members of the scientific and technical teams focused on clinical strategy, translational medicine, multimodal biology, and the application of foundation models in oncology and immunology.

Offer: Following the completion of the interviews, our hiring team will make a final decision and will be in touch to share the outcome of your interviews. If the team would like to move forward, the recruiter will discuss the details of our proposed offer with you.

Onboarding: We are happy to have you joining the team. Once you have accepted and signed your offer, we will be in touch to begin the process of onboarding you to Bioptimus.

Why This is a Unique Opportunity

You will:

• Support the clinical and scientific strategy behind next-generation foundation models in biology.
• Work at the intersection of AI, oncology, immunology, and multimodal biomedical research.
• Collaborate with scientific, data, and partnerships teams on clinically relevant research initiatives.
• Contribute to the development of clinically grounded approaches to biomedical AI.
  
  

And benefit from:

• A collaborative and mission-driven work environment.
• Competitive salary and equity package.
• Flexible work arrangements, including remote options.
• Opportunities for professional growth and leadership development.
• Shape the future of biology and AI by contributing to groundbreaking work.
  
  

We believe that the unique contributions of all Bioptimists create our success. To ensure that our culture continues to incorporate everyone’s perspectives and experience, we never discriminate based on race, religion, national origin, gender identity or expression, sexual orientation, age, or marital, or disability status. Decisions related to hiring are made fairly, and we provide equal employment opportunities to all qualified candidates. We take responsibility for always striving to create an inclusive environment that makes every employee and candidate feel welcome.