1 researcher position in bioinformatic metabolomics data analysis
SciLifeLabSweden1 day ago
Full-timeResearch, Analyst +1
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Uppsala University, Disciplinary Domain of Science and Technology, Faculty of Chemistry, Department of Chemistry – BMC
The Department of Chemistry – BMC conducts research and education in analytical chemistry, biochemistry and organic chemistry. More than 100 people, including around 45 PhD students, work at the department. New employees and students are recruited from all over the world and English is the main working language. The department is located at the Biomedical Centre in Uppsala, which facilitates collaborations with research groups in biology, pharmacy, medicine and SciLifeLab and gives access to advanced infrastructure for experimental and theoretical studies. The international environment and good opportunities for interdisciplinary collaborations enables PhD students at the department to participate in relevant research projects and prepare for an international research career.
Read more about the research at The Department of Chemistry – BMC at our website.
Uppsala University is a leading international research institution, with more than 53,000 students and 7,600 employees. We offer an inspiring academic environment with world-class infrastructure and a strong commitment to top-tier research, education, and societal engagement. Uppsala University is one of the four founding institutions of Science for Life Laboratory (SciLifeLab), a nationally recognized center for infrastructure and research in translational medicine and molecular biosciences.
Read more
As part of this initiative, the SciLifeLab Drug Discovery and Development Platform (SciLifeLab DDD) was created to support academic drug discovery in Sweden. Within this platform, the ADME of Therapeutics (ADMEoT) — also known as Uppsala University Drug Optimization and Pharmaceutical Profiling (UDOPP) — operates as a specialized unit in the Department of Pharmacy, Faculty of Pharmacy. The unit focuses on in vitro ADME (Absorption, Distribution, Metabolism, and Excretion), bioanalysis, and pharmacokinetic (PK) profiling during early drug discovery.
More information: https://www.uu.se/en/department/pharmacy/infrastructure/udopp
The Department of Pharmacy at Uppsala University offers an interdisciplinary environment at the forefront of pharmaceutical sciences. With cutting-edge research, top-tier education, and extensive collaborations, we are a key force in the field. Our core competencies include in vitro ADME models, advanced in vivo methods, computational modeling and simulation, as well as patient-focused and policy-related studies, ranging from individual drug optimization to pharmaceutical policy analysis.
More about our research: https://www.uu.se/institution/farmaci
Project description
The ADMEoT unit at the SciLifeLab DDD, in collaboration with the Laboratory of Professor Daniel Globisch (Department of Chemistry-BMC), Uppsala university, is establishing a dedicated Metabolomics Capability for Drug Discovery. The researcher position is available for the development and maintenance of a robust bioinformatics metabolomics data analysis platform for the investigation of drug-related metabolism. The position will be located at the Globisch laboratory (https://www.globischlab.org) in the Department of Chemistry-BMC in very close collaboration with the ADMEoT unit as part of the SciLifeLab DDD platform in the Department of Pharmacy. This highly interdisciplinary platform will include data analysis in a close and direct collaboration with an Analytical Chemistry researcher at the Department of Pharmacy. You will support ongoing and future Swedish academic drug discovery and development projects by providing metabolomics expertise and push the field of pharmacometabolomics forward. You will also serve as the metabolomics expert in interdisciplinary teams, including within the Chemistry Department of Pharmacy and SciLifeLab DDD. We are searching for a highly motivated researcher with passion and enthusiasm for science to build up and maintain the bioinformatics metabolomics analysis platform.
Duties
The successful candidate will build, implement and maintain robust bioinformatics pipelines for the metabolomics data analysis and visualization of metabolomics data, support the integration of software tools for data (pre-)processing, biomarker discovery, and predictive modelling. Furthermore, serve as the metabolomics subject-matter expert within interdisciplinary teams spanning from the Globisch Laboratory at the Department of Chemistry – BMC, the ADMEoT unit at the Department of Pharmacy, and SciLifeLab DDD. The role entails close collaboration with researchers across multiple institutions in Sweden and internationally. The position includes close work within ongoing and future Swedish academic drug discovery projects, and thus, interdisciplinary collaboration within respective DD project teams.
Requirements
The successful candidate must hold a PhD degree with documented substantial experience in metabolomics data analysis. The required expertise includes raw UPLC-MS-collected data preprocessing with XCMS, MZmine or MSDIAL, normalization procedures, proficiency in R and/or Python for scripting and data analysis, metabolite ID via MS/MS and annotation (e.g. SIRIUS, HMDB, authentic libraries etc.), statistical uni- and multivariate analysis, data visualization (PCA score, volcano, heatmap, and correlation plots, either software-or script-based), and metadata integration. Demonstrated expertise in both untargeted and targeted metabolomics workflows and strong understanding of statistics and statistical modeling applied to metabolomics are required. Demonstrated ability to work in interdisciplinary teams and integrate metabolomics with biological and pharmacological datasets are expected.
Great emphasis will be placed on personal qualities such as good collaborative skills, motivation and independence with a collaborative, team-oriented mindset. Additionally, how the applicant through his/her experience and competence is judged to have the abilities necessary to develop within the project. Good English speaking, reading and writing skills are required.
Additional Qualifications
The employment is a permanent position (a probationary period of 6 months will be applied). Scope of employment 100 %. Starting date: 2025-12-01 or as otherwise agreed. Placement: Uppsala.
For further information about the position, please contact: Professor Daniel Globisch, [email protected], +46 18 471 36 30 (SciLifeLab DDD Scientific Platform Director) and/or Assoc. Prof. Pawel Baranczewski: [email protected] +46 707 467894 (Head of ADME of Therapeutics Unit).
Please submit your application by October 20th, 2025, UFV-PA 2025/2891.
Uppsala University is a broad research university with a strong international position. The ultimate goal is to conduct education and research of the highest quality and relevance to make a difference in society. Our most important asset is all of our 7,600 employees and 53,000 students who, with curiosity and commitment, make Uppsala University one of Sweden’s most exciting workplaces.
Read more about our benefits and what it is like to work at Uppsala University
https://uu.se/om-uu/jobba-hos-oss/
The position may be subject to security vetting. If security vetting is conducted, the applicant must pass the vetting process to be eligible for employment.
Please do not send offers of recruitment or advertising services.
Submit your application through Uppsala University’s recruitment system.
The Department of Chemistry – BMC conducts research and education in analytical chemistry, biochemistry and organic chemistry. More than 100 people, including around 45 PhD students, work at the department. New employees and students are recruited from all over the world and English is the main working language. The department is located at the Biomedical Centre in Uppsala, which facilitates collaborations with research groups in biology, pharmacy, medicine and SciLifeLab and gives access to advanced infrastructure for experimental and theoretical studies. The international environment and good opportunities for interdisciplinary collaborations enables PhD students at the department to participate in relevant research projects and prepare for an international research career.
Read more about the research at The Department of Chemistry – BMC at our website.
Uppsala University is a leading international research institution, with more than 53,000 students and 7,600 employees. We offer an inspiring academic environment with world-class infrastructure and a strong commitment to top-tier research, education, and societal engagement. Uppsala University is one of the four founding institutions of Science for Life Laboratory (SciLifeLab), a nationally recognized center for infrastructure and research in translational medicine and molecular biosciences.
Read more
As part of this initiative, the SciLifeLab Drug Discovery and Development Platform (SciLifeLab DDD) was created to support academic drug discovery in Sweden. Within this platform, the ADME of Therapeutics (ADMEoT) — also known as Uppsala University Drug Optimization and Pharmaceutical Profiling (UDOPP) — operates as a specialized unit in the Department of Pharmacy, Faculty of Pharmacy. The unit focuses on in vitro ADME (Absorption, Distribution, Metabolism, and Excretion), bioanalysis, and pharmacokinetic (PK) profiling during early drug discovery.
More information: https://www.uu.se/en/department/pharmacy/infrastructure/udopp
The Department of Pharmacy at Uppsala University offers an interdisciplinary environment at the forefront of pharmaceutical sciences. With cutting-edge research, top-tier education, and extensive collaborations, we are a key force in the field. Our core competencies include in vitro ADME models, advanced in vivo methods, computational modeling and simulation, as well as patient-focused and policy-related studies, ranging from individual drug optimization to pharmaceutical policy analysis.
More about our research: https://www.uu.se/institution/farmaci
Project description
The ADMEoT unit at the SciLifeLab DDD, in collaboration with the Laboratory of Professor Daniel Globisch (Department of Chemistry-BMC), Uppsala university, is establishing a dedicated Metabolomics Capability for Drug Discovery. The researcher position is available for the development and maintenance of a robust bioinformatics metabolomics data analysis platform for the investigation of drug-related metabolism. The position will be located at the Globisch laboratory (https://www.globischlab.org) in the Department of Chemistry-BMC in very close collaboration with the ADMEoT unit as part of the SciLifeLab DDD platform in the Department of Pharmacy. This highly interdisciplinary platform will include data analysis in a close and direct collaboration with an Analytical Chemistry researcher at the Department of Pharmacy. You will support ongoing and future Swedish academic drug discovery and development projects by providing metabolomics expertise and push the field of pharmacometabolomics forward. You will also serve as the metabolomics expert in interdisciplinary teams, including within the Chemistry Department of Pharmacy and SciLifeLab DDD. We are searching for a highly motivated researcher with passion and enthusiasm for science to build up and maintain the bioinformatics metabolomics analysis platform.
Duties
The successful candidate will build, implement and maintain robust bioinformatics pipelines for the metabolomics data analysis and visualization of metabolomics data, support the integration of software tools for data (pre-)processing, biomarker discovery, and predictive modelling. Furthermore, serve as the metabolomics subject-matter expert within interdisciplinary teams spanning from the Globisch Laboratory at the Department of Chemistry – BMC, the ADMEoT unit at the Department of Pharmacy, and SciLifeLab DDD. The role entails close collaboration with researchers across multiple institutions in Sweden and internationally. The position includes close work within ongoing and future Swedish academic drug discovery projects, and thus, interdisciplinary collaboration within respective DD project teams.
Requirements
The successful candidate must hold a PhD degree with documented substantial experience in metabolomics data analysis. The required expertise includes raw UPLC-MS-collected data preprocessing with XCMS, MZmine or MSDIAL, normalization procedures, proficiency in R and/or Python for scripting and data analysis, metabolite ID via MS/MS and annotation (e.g. SIRIUS, HMDB, authentic libraries etc.), statistical uni- and multivariate analysis, data visualization (PCA score, volcano, heatmap, and correlation plots, either software-or script-based), and metadata integration. Demonstrated expertise in both untargeted and targeted metabolomics workflows and strong understanding of statistics and statistical modeling applied to metabolomics are required. Demonstrated ability to work in interdisciplinary teams and integrate metabolomics with biological and pharmacological datasets are expected.
Great emphasis will be placed on personal qualities such as good collaborative skills, motivation and independence with a collaborative, team-oriented mindset. Additionally, how the applicant through his/her experience and competence is judged to have the abilities necessary to develop within the project. Good English speaking, reading and writing skills are required.
Additional Qualifications
- Practical experience in a laboratory environment is considered a merit.
- Qualifications that will be considered an advantage include, hands-on experience with metabolomic investigations in a laboratory setting and experience in project management.
The employment is a permanent position (a probationary period of 6 months will be applied). Scope of employment 100 %. Starting date: 2025-12-01 or as otherwise agreed. Placement: Uppsala.
For further information about the position, please contact: Professor Daniel Globisch, [email protected], +46 18 471 36 30 (SciLifeLab DDD Scientific Platform Director) and/or Assoc. Prof. Pawel Baranczewski: [email protected] +46 707 467894 (Head of ADME of Therapeutics Unit).
Please submit your application by October 20th, 2025, UFV-PA 2025/2891.
Uppsala University is a broad research university with a strong international position. The ultimate goal is to conduct education and research of the highest quality and relevance to make a difference in society. Our most important asset is all of our 7,600 employees and 53,000 students who, with curiosity and commitment, make Uppsala University one of Sweden’s most exciting workplaces.
Read more about our benefits and what it is like to work at Uppsala University
https://uu.se/om-uu/jobba-hos-oss/
The position may be subject to security vetting. If security vetting is conducted, the applicant must pass the vetting process to be eligible for employment.
Please do not send offers of recruitment or advertising services.
Submit your application through Uppsala University’s recruitment system.
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