MindWalk Corp. (formerly BioStrand)
Data Scientist Antibody Discovery
MindWalk Corp. (formerly BioStrand)Belgium5 days ago
Full-timeEngineering, Information Technology
IPA (ImmunoPrecise Antibodies) is a Contract Research Organization (CRO) with end-to-end technology solutions empowering clients in the discovery and development of antibody therapeutics and diagnostics. We serve our partners through a multi-national, integrated network of facilities in North America and Europe. This enables us to offer a comprehensive range of antibody discovery and development services including, for example, custom antibody generation, in silico analysis, antibody characterization, engineering, manufacturing, and humanization. Located in North America and Europe, IPA serves many of the world’s top biotech and pharmaceutical companies in the common mission of conquering life-threatening diseases.

Job Description

At BioStrand, data scientists are the heart of our organisation. You have an active role in the development and deployment of new in silico predictive models for antibody discovery. You identify and engineer key attributes of therapeutic antibodies, including in silico affinity modulation and mitigation of sequence liabilities. You collaborate with colleagues across the sites in the Netherlands and Canada, a large interdisciplinary team of scientists and program leaders, to ensure continuous integration of in silico and wet-lab knowledge. At Biostrand, you will be part of the Data Science team and work in close collaboration with the Software and Front-End team. Together with the Head of Innovation you will make up a roadmap with a set of deliverables.

Key Responsibilities Shall Include

  • You identify and engineer key attributes of therapeutic antibodies, including in silico affinity modulation and mitigation of sequence liabilities.
  • You collaborate with colleagues across the sites in the Netherlands and Canada, a large interdisciplinary team of scientists and program leaders, to ensure continuous integration of in silico and wet-lab knowledge.
  • Together with the Head of Innovation you will make up a roadmap with a set of deliverables.

Requirements

  • Education: You are an expert in structural biology and antibody discovery and engineering. You have a PhD Degree in that domain and preferably some years of experience working in antibody discovery within Pharma and Biotech.
  • You have practical knowledge of various machine learning techniques, preferably deep learning, including graph neural networks (GNNs), clustering and feature engineering.
  • You speak Python and have used a number of data science specific packages.
  • You are able to advise, deploy, configure and automate the most suitable AWS service (using terraform);
  • You have a strong interest in bioinformatics applications, cloud computing and are skilled in data visualization.
  • In our team we go off the beaten track every day and nothing we come up with is standard. You have to be a strategic and creative thinker. You work efficiently, are a real team player and deliver high-quality results on time.
  • You have good written and oral communication skills in English.
  • In our team we go off the beaten track every day and nothing we come up with is standard. You have to be a strategic and creative thinker. You work efficiently, are a real team player and deliver high-quality results on time.

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